Best Compliance Automation Software for Healthcare in 2025

Compliance in healthcare is not just a checkbox but it is a lifeline. From HIPAA to HITECH to NIST, providers are constantly under pressure to protect patient data while keeping up with evolving regulations. But in 2025, the old ways of managing compliance which included manual logs, endless spreadsheets, and scattered policies just don’t cut it anymore.

Compliance automation software is the way ahead. These tools automate tasks and make it easy to stay compliant, monitor devices, track policy violations, manage access, and keep everything audit-ready without burdening your IT or security teams.

Let’s have a look at the top five compliance automation solutions for healthcare in 2025.

1. Scalefusion Veltar

Scalefusion is the best UEM software available in the market. With Veltar, its endpoint security and compliance solution’s capabilities, Scalefusion has carved a strong niche in the healthcare space by turning device management into a full-blown compliance engine. It is useful for organizations, hospitals, clinics, and labs that use different types of OS devices such as Android, IOS, MacOS, Windows, Linux, or rugged devices to deliver care.

Unlike traditional UEM tools, Scalefusion puts compliance front and center automating policy enforcement, securing endpoints, and flagging issues in real time.

Key Features:

• Automate CIS Compliance: Enforce CIS compliance across endpoints to set a strong foundational security layer.
• Real-Time Monitoring: Instantly detect and respond to risky behavior or fix policies.
• Policy groups: Deploy compliance at scale with dynamic policy grouping. Assign rules based on device types and OS versions.
• Intelligent auto-remediation: Instantly fix non-compliant configurations and reduce IT workload with self-correcting security policies.
• Audit Reports: Access device histories, user actions, and compliance logs within a few clicks.

Pricing:

Pricing depends on the requirements, with enterprise plans offering advanced analytics, integrations, and dedicated support.

2. ComplyAssistant

ComplyAssistant is built for healthcare from the ground up. It is more than a policy tracker, it is a full compliance project management tool. Think of it as a command center to manage HIPAA audits, vendor agreements, and risk assessments without switching between tools.

Key Features:

• Prebuilt risk templates aligned with HIPAA and HITECH
• Centralized repository for policies and procedures
• Task tracking with automated reminders
• Vendor management and BAA tracking

Pricing: Available via custom quotes depending on organization size and needs. Best suited for healthcare providers with compliance-heavy operations.

3. Hyperproof

Hyperproof provides a simple interface and strong multi-framework support, which makes it a great fit for healthcare organizations to easily manage multiple compliance standards such as HIPAA, HITRUST, ISO 27001, and more. It helps compliance teams to reduce redundant work by mapping controls across multiple frameworks at once.

Key Features:

• Continuous compliance checks with real-time integrations
• Evidence collection and automated document versioning
• Smart mapping of controls across multiple frameworks
• Strong collaboration tools for cross-team projects

Pricing: Plans start from $20/user/month. This tool is suitable for organizations that want to centralize compliance.

4. Predict360 by 360factors

Predict360 brings AI into the compliance game. It does not just track but also predicts what could go wrong. Built with Governance, Risk, and Compliance in mind, Predict360 is a good solution for larger healthcare systems and insurers who need strong compliance and enterprise risk management capabilities.

Key Features:

• AI-powered risk scoring and forecasting
• Policy lifecycle automation
• Incident tracking and response workflows
• Built-in training and certification management

Pricing: Custom pricing. Expect it to lean on the higher end, but the depth and predictive capabilities justify it for complex environments.

5. Secureframe

If you are a telehealth startup or digital health app provider, Secureframe is a great entry point. It is fast to set up, has intuitive dashboards, and automated workflows for HIPAA and HITRUST. It is helpful for tech-heavy teams who need to scale compliance without spending extra on setting up a security department.

Key Feature:

• HIPAA-ready policy templates and control libraries
• Automated security checks in your cloud environment
• Built-in staff training and certification tools
• Audit-ready reports with real-time data

Pricing: Starts at $1,000/year, with plans depending on the number of frameworks and users.

Final Verdict: Which Tool is the Best?

All five solutions bring real value to the table. Hyperproof offers strong flexibility. Predict360 is a powerhouse for risk-driven operations. ComplyAssistant simplifies documentation-heavy processes. Secureframe is perfect for smaller, agile teams.

But when it comes to balancing real-time policy enforcement, scalable device security, and hands-off compliance monitoring in healthcare environments, Scalefusion Veltar quietly steals the show. It automates compliance, simplifies everyday device management which results in fewer gaps, faster remediation, and a smoother experience for your IT team. 

Are you looking to protect your endpoints and automate healthcare compliance? Book your 14-day free trial with Scalefusion Veltar and see how it makes it easy to stay secure, compliant, and ready for audits anytime.

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